The industry pundits are suggesting and predicting a solution such as SquareAnswer.  Please see the two excerpts below;

 
2004 Technology Readiness Survey
University of Maryland - R.H. School of Business
Summary Report - February 3, 2005

 "In the future, such solutions may become practical as technology advances in the area of authentication that can flag whether a sender has provided proper identification.  Users would be assured that a sender is legitimate, or that the sender can at least be tracked if they engage in illicit activities, so they may actually read more mail."  Full Story

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Tom Spring, PC World
Monday, January 24, 2005

 "Strive for Inbox Efficiency -- You may not be able to judge a book by its cover, but you can often judge an e-mail by its subject line. And important messages with uninformative or vague subject lines can get lost in crowded inboxes.  One way to rise above the e-mail din is by providing short, specific information in your subject line: for example, "Please Call Me ASAP: 555-555-5555" or "Proposal is in the Mail." Full Story